The glycosaminoglycans of human tracheobronchial cartilage
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چکیده
منابع مشابه
Changes with age in the glycosaminoglycans of human articular cartilage.
Human articular cartilage was obtained post mortem from the lateral femoral condyles of 30 subjects aged from under 1 to 70 years. Cryostat sections taken 0--100 micrometers and 900--100 micrometers deep to the cartilage surface were exhaustively extracted to recover the glycosaminoglycans (GAG). After fractionation by cellulose acetate electrophoresis and enzyme depolymerisation individual GAG...
متن کاملContents and compositions of glycosaminoglycans in different sites of the human hip joint cartilage.
The distribution of glycosaminoglycans (GAGs) in different functional regions (weight-bearing and nonweight-bearing portions) of the human hip joint cartilage was studied. The results obtained were as follows: (1) Weight-bearing cartilage contains larger amounts of GAGs than nonweight-bearing, cartilage. (2) Weight-bearing cartilage contains keratan sulphate in higher ratio to chondroitin sulph...
متن کاملThe glycosaminoglycans of human plasma.
A method is proposed for the measurement of glycosaminoglycans (GAG) on 5-10 ml of plasma. It is based on the adsorption of GAG on small ECTEOLA columns followed by measurement of the hexuronic acid in the NaCl eluates. Routine use of the method has indicated the presence of a GAG fraction that adsorbs readily on ECTEOLA ("free" GAG) and of another that adsorbs on it only after treatment with p...
متن کاملExtraction of cartilage glycosaminoglycans: a comparison of ten solvents.
confirming that the binding of PI in the absence of Mn2+ is reversible. This was also demonstrated by the fact that it was possible to separate I 32PlPl completely from the enzyme by Sephadex G-100 gel filtration. When Pi followed by MnZ+ was added to the enzyme, dialysis did not restore activity. However, a substantial proportion of the activity reappeared during storage after dialysis, sugges...
متن کاملTowards a Multi-Scale Model of Cartilage: Coarse-Graining Glycosaminoglycans
Background: Articular cartilage is an avascular tissue that serves to reduce the frictional load between contacting bones in load bearing joints. The tissue consists of a sparse population of chondrocytes (≈ 2% by volume) embedded in an extracellular matrix (ECM). Aggrecan and type-II-collagen are the two primary macromolecules constituting the ECM and play distinct yet complementary biomechani...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1970
ISSN: 0306-3283
DOI: 10.1042/bj1200777